Christianity is an Abrahamic, monotheistic religion based on the life and teachings of Jesus of Nazareth. It is the world's largest religion, with about 2.5 billion followers. Its adherents, known as Christians, make up a majority of the population in 157 countries and territories, and believe that Jesus is the Christ, whose coming as the Messiah was prophesied in the Hebrew Bible (called the Old Testament in Christianity) and chronicled in the New Testament.
Christianity began as a Second Temple Judaic sect in the 1st century in the Roman province of Judea. Jesus' apostles and their followers spread around the Levant, Europe, Anatolia, Mesopotamia, the South Caucasus, Egypt, and Ethiopia, despite initial persecution. It soon attracted gentile God-fearers, which led to a departure from Jewish customs, and, after the Fall of Jerusalem, AD 70 which ended the Temple-based Judaism, Christianity slowly separated from Judaism. Emperor Constantine the Great decriminalized Christianity in the Roman Empire by the Edict of Milan (313), later convening the Council of Nicaea (325) where Early Christianity was consolidated into what would become the State church of the Roman Empire (380). The early history of Christianity's united church before major schisms is sometimes referred to as the "Great Church" (though divergent sects existed at the same time, including Gnostics and Jewish Christians). The Church of the East split after the Council of Ephesus (431) and Oriental Orthodoxy split after the Council of Chalcedon (451) over differences in Christology, while the Eastern Orthodox Church and the Catholic Church separated in the East–West Schism (1054), especially over the authority of the bishop of Rome. Protestantism split in numerous denominations from the Catholic Church in the Reformation era (16th century) over theological and ecclesiological disputes, most predominantly on the issue of justification and the primacy of the bishop of Rome. Christianity played a prominent role in the development of Western civilization, particularly in Europe from late antiquity and the Middle Ages.Following the Age of Discovery (15th–17th century), Christianity was spread into the Americas, Oceania, sub-Saharan Africa, and the rest of the world via missionary work.